Vogt-Koyanagi-Harada Syndrome
نویسندگان
چکیده
97 Vogt-Koyanagi-Harada syndrome is generally a rare multisystemic autoimmune disorder involving with pigmented structures, such as the eye, meninges, inner ear and skin. The syndrome typically presents as an episode of bilateral panuveitis after prodromal symptoms similar to aseptic meningitis. Auditory disturbances include tinnitus, hearing loss and vertigo. We report the case of a 74-year-old woman with blurred vision, two month history of sudden onset hearing loss and tinnitus in the right ear.
منابع مشابه
Applicability of the 2001 revised diagnostic criteria in Brazilian Vogt-Koyanagi-Harada disease patients.
PURPOSE To determine the applicability of the international revised diagnostic criteria for Vogt-Koyanagi-Harada disease. METHODS Retrospective study. Medical charts of 140 patients with the diagnosis of Vogt-Koyanagi-Harada disease, from the Uveitis Sector of the Federal University of Sao Paulo (UNIFESP), were revised and classified following the revised diagnostic criteria. RESULTS Of the...
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Vogt-Koyanagi-Harada syndrome is an acquired illness with ocular, cutaneous, and/or neurologic features. A 4-year-old child who acutely developed visual disturbances and headache and was found to have serous retinal detachments and aseptic meningitis is presented. Improvement was rapid with corticosteroid therapy. This is the youngest reported patient with Vogt-Koyanagi-Harada syndrome.
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We describe herein 2 patients who developed Vogt-Koyanagi-Harada syndrome in the course of renal biopsy-proven immunoglobulin A (IgA) nephropathy. A 61-year-old man with an 11-year history of IgA nephropathy and a 16-year history of thyroiditis, and a 56-year-old man with a 5-year history of IgA nephropathy developed Vogt-Koyanagi-Harada syndrome. At the time of the eye disease presentation, Ig...
متن کاملVogt-Koyanagi-Harada disease.
Vogt-Koyanagi-Harada (VKH) disease, also known as uveomeningitic syndrome, is an idiopathic multisystem inflammatory disease with bilateral uveitis. Patients with bilateral anterior uveitis with vitiligo, poliosis, alopecia, and dysacousia were first described by Vogt in 1906 and then Koyanagi in 1929. Harada described a case of posterior uveitis with exudative retinal detachment and pleocytosi...
متن کاملNew insights into Vogt-Koyanagi-Harada disease.
Vogt-Koyanagi-Harada disease (VKH), a well-established multiorgan disorder affecting pigmented structures, is an autoimmune disorder of melanocyte proteins in genetically susceptible individuals. Several clinical and experimental data point to the importance of the effector role of CD4+ T cells and Th1 cytokines, the relevance of searching a target protein in the melanocyte, and the relevance o...
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1. Moorthy RS, Inomata H, Rao NA. Vogt-KoyanagiHarada syndrome. Surv Ophthalmol 1995;39:265-92. 2. Yamaki K, Gocho K, Hayakawa K, Kondo I, Sakuragi S. Tyrosinase family proteins are antigens specific to Vogt-Koyanagi-Harada disease. J Immunol 2000;165:7323-9. 3. Read RW, Holland GN, Rao NA, Tabbara KF, Ohno S, ArellanesGarcia L, et al. Revised diagnostic criteria for Vogt-Koyanagi-Harada diseas...
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